WASHINGTON — Republicans will hold on to their majority in the U.S. House and regain control of the Senate when Congress convenes in January, setting the party up to potentially make major policy changes during the next two years.

Republicans have secured their monopoly on power in Donald Trump’s new Washington, retaining their majority in the House of Representatives, CNN projected Wednesday, after picking up seats in California and Arizona and ushering in a dramatic new era of right-wing populist rule.